Investigating genetic regulation in the human placenta, while sipping on my flat white.
Big fan ofggplot2
and Jazz music. Jack-of-all-Trades kinda person
A PhD Candidate in the Medical Genetics Graduate Program at The University of British Columbia, I currently reside in the lovely and vibrant city of Vancouver in British Columbia, Canada.
My research interests lie in developmental, cardiovascular, and population genetics. My curiosity is driven by wanting to elucidate the genetic differences that exist between populations of different ancestries.
I firmly believe that the more you give, the more you get, and as such, I try to give back as much as I can to the community.
I’m an avid bibliophile, coffee enthusiast, and culinary aficionado. I also make and sell custom genetics-themed graphics and merchandise on Etsy!
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View my latest Academic CV
Last updated: October 2024
Latest Highlights:
Research Background:
Genomics and bioinformatics -
developmental/embryonic genetics, cardiovascular genetics, epidemiology,
lung and liver cancer, RNA, biostatistics
Programming:
R/RMarkdown/R Shiny, Linux/BASH, HPC,
Git/GitHub, Jupyter
Database Usage:
NCBI, OMIM, GEO, UCSC Genome Browser,
ClinVar, GeneCards, UniProt, GTex, miRBase, RNACentral
Genomics Analysis Tools:
IGV, PLINK, GEMMA,
miRMaster
Data Types:
GWAS Summary Statistics/SNP (UK/China
Kadoorie/Japan Biobanks), RNA sequencing (total and small), single-cell
RNA sequencing (scRNA-seq), DNA methylation (850/450K)
The University of British Columbia, Canada
(2019 - )
Thesis Project: Characterizing
small non-coding RNAs in the Human Placenta.
Dr. Wendy Robinson - BC
Children’s Hospital Research Institute | Lab Website
Dr. Wan Lam - BC Cancer
Research Centre | Lab Website
Awards:
IFPA New Investigator Award 2024 – International Federation of Placenta Associations (IFPA)
4 Year Doctoral Fellowship (4YF) Award (2020-2024) – The University of British Columbia
The James Miller Memorial Prize - Department of Medical Genetics, The University of British Columbia
President’s Academic Excellence Initiative PhD Award (2020-2024) – The University of British Columbia
International Tuition Award (2019-2024) – The University of British Columbia
Diversity Scholar 2022 - RStudio PBC
Trainee Travel Grant 2022 - BC Children’s Hospital Research Institute
Virtual Knowledge Exchange Grant 2021 – BC Children’s Hospital Research Institute
Selected Publications:
View all on Google Scholar or ORCiD.
Telkar N, Stewart GL, Pewarchuk ME, Cohn DE, Robinson WP, Lam WL. (2022). Small Non-Coding RNAs in the Human Placenta: regulatory roles and clinical utility. Frontiers in Genetics; 13.
Rees WD, Telkar N, Lin D, Peloni C, Fathi A, Kobor M, Zachos N, Steiner T. (2022). An in vitro chronic damage model impairs inflammatory and regenerative responses in human colonoid monolayers. Cell Reports; 38(3)
Martinez VD, Cohn DE, Telkar N, Minatel BC, Pewarchuk ME, Marshall EA, Price ME, Robinson WP, Lam WL. (2021). Profiling the Small Non-Coding RNA Transcriptome of the Human Placenta.. 2021. Sci Data; 8, 166.
Zhao G, Zhang HM, Nasseri AR, Yip F, Telkar N, Chen YT, Aghakeshmiri S, Küper C, Lam W, Yang W, Zhao J, Luo H, McManus BM, Yang D. (2024). Heart-specific NFAT5 knockout suppresses type I interferon signaling and aggravates coxsackievirus-induced myocarditis. Basic Res Cardiol
Souza VGP, Telkar N, Lam WL, Reis PP. (2024). Comprehensive Analysis of Lung Adenocarcinoma and Brain Metastasis through Integrated Single-Cell Transcriptomics. International Journal of Molecular Sciences; 25(7), 3779
In Revisions - Rolf N, Liu LYT, Leclair P, Lorentzian AC, Atre T, Farrokhi A, Telkar N, Casazza W, Vercauteren SM, Lange PF, Maxwell CA, Lim CJ, Reid GSD (2024). Immunophenotype shifts during childhood acute lymphoblastic leukemia (ALL) relapse progression result from changing abundance levels of phenotypically distinct subpopulations.
Submitted - Telkar N, Stewart GL, Minatel BC, Cohn DE, Benard K, Souza VGP, Pewarchuk ME, Martinez VD, Reis PP, Robinson WP, Lam WL. Reactivation of human fetal microRNAs in liver cancer.
Submitted - Telkar N, Hui D, Peñaherrera MS, Yuan V, Martinez VD, Stewart GL, Beristain AG, Lam WL, Robinson WP. Profiling the cell-specific small non-coding RNA transcriptome of the human placenta.
Communication:
Selected Presentation within ‘New Technologies in Cancer Genetics’ at the European Society of Human Genetics (ESHG) 2023 Conference
The University of Toronto Health Network (UHN) Seminar Series - Invited
ONCO548: Knowledge Translation, Interdisciplinary Oncology Program, UBC - Invited
University College London, London, England
Wellcome Sanger Institute, Cambridge, London
(2017 - 2018)
Dissertation: Comparing the
Genetic Architecture of Lipid Traits between Populations
Supervisor: Dr. Karoline
Kuchenbaecker
Publication:
Kuchenbaecker K, Telkar N,
Reiker T, et al. The transferability of
lipid loci across African, Asian and European cohorts. 2019. Nature
Communications; 10: 4330.
The University of Newcastle upon Tyne, England
(2014 -2017)
Dissertation: Genome-wide RNAi Screening to identify new genes involved in Mitochondrial Disease
Awards:
Genes and Development Summer Studentship 2016 – The Genetics Society UK
Faculty of Medical Sciences Undergraduate Research Scholarship 2016 – Newcastle University
Commendation Award – Newcastle University Student Research Scholarships and Expeditions 2016
Second Place Poster Award 2016 – Newcastle University Faculty of Medicine
ncl+ Award – Newcastle University (for extracurricular achievement)
Publications:
Front Row Ventures, British Columbia, Canada (October 2023 - )
Nucleate: Canada Chapter, Canada (November 2023 - )
Pillar VC, Boston (August 2024)
Nucleate Genesis, Canada (February - May 2024)
BenchSci, Toronto, Canada (April 2022 - October 2023)
adMare BiInnovations, Canada (April - June 2023)
Trainee Omics Group (TOG) Committee, BC Children’s Hospital Research Institute (September 2021 - Present)
BC Children’s Hospital Research Institute, Vancouver, Canada (Jan - June 2021)
The University of British Columbia, Canada (Sept - Dec 2020)
"the best TA he's ever worked with"
by the Head
of the Medical Genetics Graduate Program :
“Nikita always responded promptly and thoughtfully to requests for advice. Her input and assistance helped guide the learning process. She did everything I think a good teacher should, and went above and beyond the time and effort I would expect from a TA. She was the best part of the course.”
MIT-ADT School of Bioengineering Sciences and Research, Pune, India (Feb - July 2019)
ScribblezbyNiki (June 2021 - )
SPIRITFUL (April - September 2019)
Department of Neuroscience, University College London (Nov 2017 - Jan 2018)
Department of Medical Genetics, UBC (2019 – Present)
Newcastle University and UBC (2015 – 2016 / 2020 – Present)
UBC Medical Genetics Graduate Student Association (January 2021 – Present)
Geneskool, Genome British Columbia (October 2019 – October 2020)
Newcastle South Asian Society (2016 – 2017)
rstudio::conf(2022), Washington D.C.
Shiny for R
web application developmentCentre for Teaching, Learning and Technology, UBC
"Nikita, your students will be lucky to have you, you make everything so easy to understand.”