Investigating genetic regulation in the human placenta, while sipping on my flat white.
Big fan ofggplot2
and Jazz music. Jack-of-all-Trades kinda person
A 3rd year PhD Candidate in the Medical Genetics Graduate Program at The University of British Columbia, I currently reside in the lovely and vibrant city of Vancouver in British Columbia, Canada.
My research interests lie in developmental, cardiovascular, and population genetics. My curiosity is driven by wanting to elucidate the genetic differences that exist between populations of different ancestries.
I’m an avid bibliophile, coffee enthusiast, and culinary aficionado. I also make and sell custom genetics-themed graphics and merchandise on Etsy!
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View my latest CV
Latest Highlights:
My first first-author journal publication
The Genetics Society Newsletter Interview
Research Background:
Genomics and bioinformatics - cardiovascular genetics, developmental/embryonic genetics, epidemiology, lung and liver cancer, RNA, biostatistics
Programming:
R/RMarkdown/R Shiny, Linux/BASH, HPC, Git/GitHub, Jupyter
Database Usage:
NCBI, OMIM, GEO, UCSC Genome Browser, ClinVar, GeneCards, UniProt, GTex, miRBase, RNACentral
Genomics Analysis Tools:
IGV, PLINK, GEMMA, miRMaster
Data Types:
GWAS Summary Statistics/SNP (UK/China Kadoorie/Japan Biobanks), RNA sequencing (total and small), single-cell RNA sequencing (scRNA-seq), DNA methylation (850/450K)
University of British Columbia, Canada
(2019 - )
Thesis Project: Characterizing small non-coding RNAs in the Human Placenta.
Dr. Wendy Robinson - BC Children’s Hospital Research Institute | Lab Website
Dr. Wan Lam - BC Cancer Research Centre | Lab Website
Awards:
Diversity Scholar 2022 - RStudio PBC
Virtual Knowledge Exchange Grant 2021 – BC Children’s Hospital Research Institute
Trainee Travel Grant 2022 - BC Children’s Hospital Research Institute
4 Year Doctoral Fellowship (4YF) Award (2020-2024) – University of British Columbia
President’s Academic Excellence Initiative PhD Award (2020-2024) – University of British Columbia
International Tuition Award (2019-2024) – University of British Columbia
Pubs:
Martinez VD, Cohn DE, Telkar N, Minatel BC, Pewarchuk ME, Marshall EA, Price ME, Robinson WP, Lam WL Profiling the Small Non-Coding RNA Transcriptome of the Human Placenta.. Sci Data 2021; 8, 166.
Cohn DE, Barros-Filho MC, Minatel BC, Pewarchuk ME, Marshall EA, Vucic EA, Sage AP, Telkar N, Stewart GL, Jurisica I, Reis PP, Robinson WP, Lam WL. Reactivation of multiple fetal miRNAs in lung adenocarcinoma. Cancers 2021, 13, 2686.
Marshall EA, Telkar N, Lam WL. Functional role of the cancer microbiome in the solid tumour niche. Current Research in Immunology 2021; 2: 1–6
Rees WD, Telkar N, Lin D, Peloni C, Fathi A, Kobor M, Zachos N, Steiner T. An in vitro chronic damage model impairs inflammatory and regenerative responses in human colonoid monolayers. Cell Reports 2022; 38(3)
Telkar N, Stewart GL, Pewarchuk ME, Cohn DE, Robinson WP, Lam WL. Small Non-Coding RNAs in the Human Placenta: regulatory roles and clinical utility. Frontiers in Genetics 2022; 13.
Minatel BC, Cohn DE, Pewarchuk ME, Barros-Filho MC, Sage AP, Stewart GL, Marshall EA, Telkar N, Martinez VD, Reis PP, Robinson WP, Lam WL. Genetic and epigenetic mechanisms deregulate the CRL2pVHL complex in hepatocellular carcinoma. International Journal of Molecular Sciences 2022, [Submitted]
Communication:
University of Toronto Health Network (UHN) Seminar Series - Invited
ONCO548: Knowledge Translation, Interdisciplinary Oncology Program, UBC - Invited
Interview with The Genetics Society UK
Interview with The Interview Portal
University College London, London, England
Wellcome Sanger Institute, Cambridge, London
(2017 - 2018)
Dissertation: Comparing the Genetic Architecture of Lipid Traits between Populations
Supervisor: Dr. Karoline Kuchenbaecker
Kuchenbaecker K, Telkar N, Reiker T, et al. The transferability of lipid loci across African, Asian and European cohorts. Nature Communications, 2019; 10: 4330.
Polygenics Risk Scores published on EMBL-EBI’s PGS Catalog
University of Newcastle upon Tyne, England
(2014 -2017)
Dissertation: Genome-wide RNAi Screening to identify new genes involved in Mitochondrial Disease
University Profile
Awards:
Genes and Development Summer Studentship 2016 – The Genetics Society UK
Faculty of Medical Sciences Undergraduate Research Scholarship 2016 – Newcastle University
Commendation Award – Newcastle University Student Research Scholarships and Expeditions 2016
Second Place Poster Award 2016 – Newcastle University Faculty of Medicine
ncl+ Award – Newcastle University (for extracurricular achievement)
Pubs:
Telkar N. Using WNT5A Expression to Characterize Development in the Human Gut. The Genetics Society News Newsletter, January 2017, Issue 76.
BenchSci, Toronto, Canada (April 2022 - )
BC Children’s Hospital Research Institute, Vancouver, Canada (Jan - June 2021)
Department of Neuroscience, University College London (Nov 2017 - Jan 2018)
ScribblezbyNiki (June 2021 - )
SPIRITFUL (April - September 2019)
Trainee Omics Group (TOG) Committee, BC Children’s Hospital Research Institute (September 2021 - Present)
Department of Medical Genetics, UBC (2019 – Present)
UBC Medical Genetics Graduate Student Association (January 2021 – Present)
Geneskool, Genome British Columbia (October 2019 – October 2020)
Newcastle University and UBC (2015 – 2016 / 2020 – Present)
Newcastle South Asian Society (2016 – 2017)
University of British Columbia, Canada (Sept - Dec 2020)
"the best TA he's ever worked with"
by the Head of the Medical Genetics Graduate Program : “Nikita always responded promptly and thoughtfully to requests for advice. Her input and assistance helped guide the learning process. She did everything I think a good teacher should, and went above and beyond the time and effort I would expect from a TA. She was the best part of the course.”
MIT-ADT School of Bioengineering Sciences and Research, Pune, India (Feb - July 2019)
Trainee Omics Group (TOG) Committee, BC Children’s Hospital Research Institute (September 2021 - Present)
Centre for Teaching, Learning and Technology, UBC
"Nikita, your students will be lucky to have you, you make everything so easy to understand.”